Neural stem cell quiescence comes to an un-sticky end

Katherine R Long, Charles Ffrench-Constant

Research output: Contribution to journalEditorialpeer-review

Abstract

Cell-cell interactions, a key feature of the stem cell niche, regulate many aspects of stem cell behaviour. N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.

Original languageEnglish
Pages (from-to)625-7
Number of pages3
JournalNature Cell Biology
Volume16
Issue number7
DOIs
Publication statusPublished - Jul 2014

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