Neural stem cell quiescence comes to an un-sticky end

Katherine R Long; Charles Ffrench-Constant

doi:10.1038/ncb3003

Neural stem cell quiescence comes to an un-sticky end

Katherine R Long, Charles Ffrench-Constant

Research output: Contribution to journal › Editorial › peer-review

Abstract

Cell-cell interactions, a key feature of the stem cell niche, regulate many aspects of stem cell behaviour. N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.

Original language	English
Pages (from-to)	625-7
Number of pages	3
Journal	Nature Cell Biology
Volume	16
Issue number	7
DOIs	https://doi.org/10.1038/ncb3003
Publication status	Published - Jul 2014

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10.1038/ncb3003

The role of N-cadherin in neural stem cells
Ffrench-Constant, C. (Principal Investigator)
Biotechnology and Biological Sciences Research Council
15/07/13 → 14/10/14
Project: Research

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title = "Neural stem cell quiescence comes to an un-sticky end",

abstract = "Cell-cell interactions, a key feature of the stem cell niche, regulate many aspects of stem cell behaviour. N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.",

author = "Long, \{Katherine R\} and Charles Ffrench-Constant",

year = "2014",

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AU - Ffrench-Constant, Charles

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AB - Cell-cell interactions, a key feature of the stem cell niche, regulate many aspects of stem cell behaviour. N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.

U2 - 10.1038/ncb3003

DO - 10.1038/ncb3003

M3 - Editorial

C2 - 24981635

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VL - 16

SP - 625

EP - 627

JO - Nature Cell Biology

JF - Nature Cell Biology

IS - 7

ER -

Neural stem cell quiescence comes to an un-sticky end

Abstract

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The role of N-cadherin in neural stem cells

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