Substantial progress has been made in understanding the neural control of movement in the past 30 years. Lower cost technology for tracking movements of the eyes and the hands has increased our understanding of these two systems and their interactions in both neurologically intact individuals and non-human primates. Nevertheless the neuropsychology of eye-hand coordination during visually-guided tasks such as reaching and grasping remains relatively understudied. This chapter reviews some of the relevant neurophysiology and neuropsychology of eye-hand coordination during visually-guided reaching. Current models emphasising coordinate transformations are discussed in light of new patient data showing a particular type of failure of eye-hand coordination during reaching.