New developments in osteoarthritis and cartilage biology

B. Poulet, Katherine Staines

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

Osteoarthritis (OA) is a degenerative joint disease and the most common form of arthritis. Characterised by articular cartilage loss, subchondral bone thickening and osteophyte formation, the OA joint afflicts much pain and disability. Whilst OA has been associated with many contributing factors, its underpinning molecular mechanisms are, nevertheless, not fully understood. Clinical management of OA is largely palliative and there is an ever growing need for an effective disease modifying treatment. This review discusses some of the recent progress in OA therapies in the different joint tissues affected by OA pathology.
Original languageEnglish
Pages (from-to)8-13
JournalCurrent Opinion in Pharmacology
Volume28
Early online date26 Feb 2016
DOIs
Publication statusPublished - Jun 2016

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