New fluorogenic substrate for the first continuous steroid sulfatase assay

M. Bilban, A. Billich, M. Auer, P. Nussbaumer

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The screening for new inhibitors of steroid sulfatase requires an efficient test system. To overcome the shortcomings of the available discontinuous fluorimetric assay, several coumarin-type compounds were investigated as potential new substrates. 3,4-Benzocoumarin 7-O-sulfate was found to have appropriate substrate properties for the establishment of the first direct continuous assay of steroid sulfatase. (C) 2000 Elsevier Science Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)967-969
Number of pages3
JournalBioorganic & Medicinal Chemistry Letters
Volume10
Issue number9
DOIs
Publication statusPublished - 1 May 2000

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