New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination

Sarah Neely; Jill Williamson; Anna Klingseisen; Lida Zoupi; Jason Early; Anna C Williams; David A Lyons

doi:10.1038/s41593-021-01009-x

New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination

Sarah Neely, Jill Williamson, Anna Klingseisen, Lida Zoupi, Jason Early, Anna C Williams, David A Lyons^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Nature Neuroscience
Early online date	14 Feb 2022
DOIs	https://doi.org/10.1038/s41593-021-01009-x
Publication status	E-pub ahead of print - 14 Feb 2022

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Neely_et_al_Remyelination-NN-2022[97]
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Cite this

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title = "New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination",

author = "Sarah Neely and Jill Williamson and Anna Klingseisen and Lida Zoupi and Jason Early and Williams, {Anna C} and Lyons, {David A}",

note = "Funding Information: We thank C. ffrench-Constant, E. Hughes and the Lyons Laboratory for feedback, the Bioresearch & Veterinary Services aquatics facility for fish care, S. Mitchell for electron microscopy assistance and C. Melendez-Vasquez for suggesting the ROCK experiment. This work was supported by Wellcome Trust Senior Research Fellowships (102836/Z/13/Z and 214244/Z/18/Z), a Medical Research Council Project Grant (MR/P006272/1) and an MS Society Innovative Grant (95) to D.A.L. S.A.N. and J.M.W. were supported by the Wellcome Trust Four-Year Ph.D. Program in Tissue Repair (grant 108906/Z/15/Z) and J.M.W. by a University of Edinburgh Ph.D. Tissue Repair Studentship Award (MRC Doctoral Training Partnership MR/K501293/1). L.Z. and A.W. were supported by an MS Society UK Centre grant. Funding Information: We thank C. ffrench-Constant, E. Hughes and the Lyons Laboratory for feedback, the Bioresearch & Veterinary Services aquatics facility for fish care, S. Mitchell for electron microscopy assistance and C. Melendez-Vasquez for suggesting the ROCK experiment. This work was supported by Wellcome Trust Senior Research Fellowships (102836/Z/13/Z and 214244/Z/18/Z), a Medical Research Council Project Grant (MR/P006272/1) and an MS Society Innovative Grant (95) to D.A.L. S.A.N. and J.M.W. were supported by the Wellcome Trust Four-Year Ph.D. Program in Tissue Repair (grant 108906/Z/15/Z) and J.M.W. by a University of Edinburgh Ph.D. Tissue Repair Studentship Award (MRC Doctoral Training Partnership MR/K501293/1). L.Z. and A.W. were supported by an MS Society UK Centre grant. Publisher Copyright: {\textcopyright} 2022, The Author(s), under exclusive licence to Springer Nature America, Inc.",

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AU - Neely, Sarah

AU - Williamson, Jill

AU - Klingseisen, Anna

AU - Zoupi, Lida

AU - Early, Jason

AU - Williams, Anna C

AU - Lyons, David A

N1 - Funding Information: We thank C. ffrench-Constant, E. Hughes and the Lyons Laboratory for feedback, the Bioresearch & Veterinary Services aquatics facility for fish care, S. Mitchell for electron microscopy assistance and C. Melendez-Vasquez for suggesting the ROCK experiment. This work was supported by Wellcome Trust Senior Research Fellowships (102836/Z/13/Z and 214244/Z/18/Z), a Medical Research Council Project Grant (MR/P006272/1) and an MS Society Innovative Grant (95) to D.A.L. S.A.N. and J.M.W. were supported by the Wellcome Trust Four-Year Ph.D. Program in Tissue Repair (grant 108906/Z/15/Z) and J.M.W. by a University of Edinburgh Ph.D. Tissue Repair Studentship Award (MRC Doctoral Training Partnership MR/K501293/1). L.Z. and A.W. were supported by an MS Society UK Centre grant. Funding Information: We thank C. ffrench-Constant, E. Hughes and the Lyons Laboratory for feedback, the Bioresearch & Veterinary Services aquatics facility for fish care, S. Mitchell for electron microscopy assistance and C. Melendez-Vasquez for suggesting the ROCK experiment. This work was supported by Wellcome Trust Senior Research Fellowships (102836/Z/13/Z and 214244/Z/18/Z), a Medical Research Council Project Grant (MR/P006272/1) and an MS Society Innovative Grant (95) to D.A.L. S.A.N. and J.M.W. were supported by the Wellcome Trust Four-Year Ph.D. Program in Tissue Repair (grant 108906/Z/15/Z) and J.M.W. by a University of Edinburgh Ph.D. Tissue Repair Studentship Award (MRC Doctoral Training Partnership MR/K501293/1). L.Z. and A.W. were supported by an MS Society UK Centre grant. Publisher Copyright: © 2022, The Author(s), under exclusive licence to Springer Nature America, Inc.

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