Abstract / Description of output
This paper reviews the potential participation of novel pathogenic mechanisms in chronic obstructive pulmonary disease (COPD) relating to aging, including oxidative stress and enhanced expression of markers of senescence in emphysematous lungs and the potential enhanced tissue destruction involving alveolar apoptosis. These insights provide new beginnings for future investigations in the pathobiology of COPD which may lead to future therapies for this condition.
| Original language | English |
|---|---|
| Pages (from-to) | 527-31 |
| Number of pages | 5 |
| Journal | Proceedings of the American Thoracic Society |
| Volume | 6 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2009 |