nf-LO: A scalable, containerised workflow for genome-to-genome lift over

Research output: Contribution to journalArticlepeer-review

Abstract

The increasing availability of new genome assemblies often comes with a paucity of associated genomic annotations, limiting the range of studies that can be performed. A common workaround is to lift over annotations from better annotated genomes. However, generating the files required to perform a liftover is computationally and labour intensive and only a limited number are currently publicly available. Here we present nf-LO (nextflow-LiftOver), a containerised and scalable Nextflow pipeline that enables liftovers within and between any species for which assemblies are available. nf-LO will consequently facilitates data interpretation across a broad range of genomic studies.

Original languageEnglish
JournalGenome Biology and Evolution
Early online date12 Aug 2021
DOIs
Publication statusE-pub ahead of print - 12 Aug 2021

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