TY - JOUR
T1 - Nithsdale schizophrenia surveys 20
T2 - Cognitive function in a catchment-area-based population of patients with schizophrenia
AU - Kelly, C.
AU - Sharkey, V.
AU - Morrison, G.
AU - Allardyce, J.
AU - McCreadie, R. G.
PY - 2000/10/31
Y1 - 2000/10/31
N2 - Background: Cognitive deficits are a core aspect of schizophrenia but there has been no study of cognitive function in a catchment-area-based population of patients with schizophrenia. Aims: To assess cognitive function in a population of patients with schizophrenia, and relate it to community functioning. Method: All patients with schizophrenia in Nithsdale, south-west Scotland, were identified (n=182). Measures of assessment were: National Adult Reading Test (NART), Mini-Mental State Examination (MMSE), Rivermead Behavioural Memory Test (RBMT), Executive Interview (EXIT), FAS Verbal Fluency and Health of the Nation Outcome Scales (HoNOS). Results: We assessed 138 patients, mean age 48 years (standard deviation (s.d.) 15). Only 14% were in-patients. The mean premorbid IQ as assessed by NART was 98 (s.d. 14); 15% of patients had significant global cognitive impairment (MMSE); 81% had impaired memory (RBMT); 25% had executive dyscontrol (EXIT); and 49% had impaired verbal fluency (FAS). Scores on the functional impairment sub-scale of HoNOS correlated with all measures of cognitive impairment. Conclusions: Cognitive dysfunction is pervasive in a community-based population of patients with schizophrenia. Declaration of interest: None.
AB - Background: Cognitive deficits are a core aspect of schizophrenia but there has been no study of cognitive function in a catchment-area-based population of patients with schizophrenia. Aims: To assess cognitive function in a population of patients with schizophrenia, and relate it to community functioning. Method: All patients with schizophrenia in Nithsdale, south-west Scotland, were identified (n=182). Measures of assessment were: National Adult Reading Test (NART), Mini-Mental State Examination (MMSE), Rivermead Behavioural Memory Test (RBMT), Executive Interview (EXIT), FAS Verbal Fluency and Health of the Nation Outcome Scales (HoNOS). Results: We assessed 138 patients, mean age 48 years (standard deviation (s.d.) 15). Only 14% were in-patients. The mean premorbid IQ as assessed by NART was 98 (s.d. 14); 15% of patients had significant global cognitive impairment (MMSE); 81% had impaired memory (RBMT); 25% had executive dyscontrol (EXIT); and 49% had impaired verbal fluency (FAS). Scores on the functional impairment sub-scale of HoNOS correlated with all measures of cognitive impairment. Conclusions: Cognitive dysfunction is pervasive in a community-based population of patients with schizophrenia. Declaration of interest: None.
UR - http://www.scopus.com/inward/record.url?scp=0033790904&partnerID=8YFLogxK
U2 - 10.1192/bjp.177.4.348
DO - 10.1192/bjp.177.4.348
M3 - Article
C2 - 11116777
AN - SCOPUS:0033790904
SN - 0007-1250
VL - 177
SP - 348
EP - 353
JO - British Journal of Psychiatry
JF - British Journal of Psychiatry
IS - OCT.
ER -