Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury

Barbara Wegiel, David J Gallo, Kathleen G Raman, Jenny M Karlsson, Brett Ozanich, Beek Y Chin, Edith Tzeng, Shakil Ahmad, Asif Ahmed, Catherine J Baty, Leo E Otterbein

Research output: Contribution to journalArticlepeer-review

Abstract

Carbon monoxide (CO) has emerged as a vascular homeostatic molecule that prevents balloon angioplasty-induced stenosis via antiproliferative effects on vascular smooth muscle cells. The effects of CO on reendothelialization have not been evaluated.
Original languageEnglish
Pages (from-to)537-48
Number of pages12
JournalCirculation
Volume121
Issue number4
DOIs
Publication statusPublished - 2010

Keywords

  • angioplasty, balloon
  • endothelium
  • nitric oxide synthase
  • signal transduction
  • stenosis

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