Nitric oxide regulation of plant metabolism

Kapuganti Jagadis Gupta*, Vemula Chandra Kaladhar, Teresa B. Fitzpatrick, Alisdair R. Fernie, Ian Max Møller, Gary J. Loake

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract / Description of output

Nitric oxide (NO) has emerged as an important signal molecule in plants, having myriad roles in plant development. In addition, NO also orchestrates both biotic and abiotic stress responses, during which intensive cellular metabolic reprogramming occurs. Integral to these responses is the location of NO biosynthetic and scavenging pathways in diverse cellular compartments, enabling plants to effectively organize signal transduction pathways. NO regulates plant metabolism and, in turn, metabolic pathways reciprocally regulate NO accumulation and function. Thus, these diverse cellular processes are inextricably linked. This review addresses the numerous redox pathways, located in the various subcellular compartments that produce NO, in addition to the mechanisms underpinning NO scavenging. We focus on how this molecular dance is integrated into the metabolic state of the cell. Within this context, a reciprocal relationship between NO accumulation and metabolite production is often apparent. We also showcase cellular pathways, including those associated with nitrate reduction, that provide evidence for this integration of NO function and metabolism. Finally, we discuss the potential importance of the biochemical reactions governing NO levels in determining plant responses to a changing environment.

Original languageEnglish
Number of pages29
JournalMolecular Plant
Early online date28 Dec 2021
DOIs
Publication statusE-pub ahead of print - 28 Dec 2021

Keywords / Materials (for Non-textual outputs)

  • hypoxia
  • metabolism
  • mitochondria
  • nitric oxide
  • pyridoxine
  • reactive nitrogen species
  • reactive oxygen species
  • S-nitrosylation

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