No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis

Graham R Campbell, Amy K Reeve, Iryna Ziabreva, Richard Reynolds, Doug M Turnbull, Don J Mahad

Research output: Contribution to journalArticlepeer-review

Abstract

Mitochondrial dysfunction is an established feature of multiple sclerosis (MS). We recently described high levels of mitochondrial DNA (mtDNA) deletions within respiratory enzyme-deficient (lacking mitochondrial respiratory chain complex IV with intact complex II) neurons and choroid plexus epithelial cells in progressive MS.
Original languageEnglish
Pages (from-to)1858-66
Number of pages9
JournalMultiple Sclerosis Journal
Volume19
Issue number14
DOIs
Publication statusPublished - Dec 2013

Fingerprint Dive into the research topics of 'No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis'. Together they form a unique fingerprint.

Cite this