Abstract / Description of output
Lymphoglandular complexes are components of the gut-associated lymphoid tissue that are characterized by submucosal lymphoid aggregates invested by projections of mucosal epithelium. Reports of pathology involving these structures are rare in both human and veterinary literature. Here we report two cases of rectal masses excised from dogs following a period of tenesmus and haematochezia. In both animals the masses were composed of lymphoid tissue closely encompassing tubuloacinar structures. Immunohistochemistry and PARR
testing demonstrated that the lymphoid population was polyclonal, comprising T and B cells arranged in loosely follicular aggregates centered on the epithelial foci. In light of these findings, a diagnosis of lymphoglandular complex nodular hyperplasia was reported. To the author’s knowledge, this is the first report of this condition in dogs.
testing demonstrated that the lymphoid population was polyclonal, comprising T and B cells arranged in loosely follicular aggregates centered on the epithelial foci. In light of these findings, a diagnosis of lymphoglandular complex nodular hyperplasia was reported. To the author’s knowledge, this is the first report of this condition in dogs.
Original language | English |
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Pages (from-to) | 1-5 |
Number of pages | 5 |
Journal | Veterinary Pathology |
Early online date | 7 Aug 2023 |
DOIs | |
Publication status | E-pub ahead of print - 7 Aug 2023 |
Keywords / Materials (for Non-textual outputs)
- Dog
- Domestic Mammals
- Species
- Gastrointestinal
- Digestive Tract
- Tissue
- Lymphoreticular
- Immunohistochemistry
- Technology
- Hyperplasia
- Histology
- Lymphoglandular complex