Non-adjustment for multiple testing in multi-arm trials of distinct treatments: rationale and justification

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Abstract

There is currently a lack of consensus and uncertainty about whether one should adjust for multiple testing in multi-arm trials of distinct treatments. A detailed rationale is presented to justify non-adjustment in this situation. We argue that non-adjustment should be the default starting position in simple multi-arm trials of distinct treatments.
Original languageEnglish
Pages (from-to)1740774520941419
JournalClinical Trials
DOIs
Publication statusPublished - 15 Jul 2020

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