Non-epithelial cellular components in eccrine spiradenoma: a histological and immunohistochemical study of 20 cases

A al-Nafussi, K Blessing, M Rahilly

Research output: Contribution to journalArticlepeer-review

Abstract

In this study, 20 cases of eccrine spiradenoma have been examined using monoclonal antibodies to identify the nature of the epithelial, as well as the non-epithelial, cellular components of this tumour. The results indicate that there is striking similarity between the epithelial cells of eccrine spiradenoma and the normal cells lining eccrine apparatus. An interesting finding was the presence of abundant T-lymphocytes and Langerhans' cells within the tumour lobules. Additionally, endothelial-lined vascular channels and neurofibrils were prominent in larger lesions.

Original languageEnglish
Pages (from-to)155-60
Number of pages6
JournalHistopathology
Volume18
Issue number2
Publication statusPublished - Feb 1991

Keywords

  • Adenoma, Sweat Gland
  • Antibodies, Monoclonal
  • Eccrine Glands
  • Epithelial Cells
  • Humans
  • Immunohistochemistry
  • S100 Proteins

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