Novel triazolothiadiazines act as potent anticancer agents in liver cancer cells through Akt and ASK-1 proteins

Medicine & Life Sciences

• Liver Neoplasms 100%
• Antineoplastic Agents 96%
• Synthetic Drugs 46%
• Quantitative Structure-Activity Relationship 45%
• Molecular Models 43%
• Catenins 42%
• Proteins 36%
• Non-Steroidal Anti-Inflammatory Agents 36%
• Cyclin D1 36%
• Cell Cycle Checkpoints 32%
• Inhibitory Concentration 50 30%
• Cell Death 25%
• Oxidative Stress 24%
• Direction compound 24%
• Epithelial Cells 23%
• Apoptosis 20%
• In Vitro Techniques 14%
• Pharmaceutical Preparations 13%
• Neoplasms 10%

Chemical Compounds

• Antineoplastic Agent 89%
• Bioactivity 72%
• Anti-Inflammatory Drug 42%
• Protein 41%
• Apoptotic 38%
• Cell Death 35%
• Oxidative Stress 33%
• Drug 17%
• Molecule 11%