Abstract
Myelinated axons are essential for rapid conduction of action potentials in the vertebrate nervous system. Of particular importance are the nodes of Ranvier, sites of voltage-gated sodium channel clustering that allow action potentials to be propagated along myelinated axons by saltatory conduction. Despite their critical role in the function of myelinated axons, little is known about the mechanisms that organize the nodes of Ranvier.
Original language | English |
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Pages (from-to) | 636-48 |
Number of pages | 13 |
Journal | Current biology : CB |
Volume | 16 |
Issue number | 7 |
DOIs | |
Publication status | Published - 2006 |