nsf is essential for organization of myelinated axons in zebrafish

Ian G Woods, David A Lyons, Matthew G Voas, Hans-Martin Pogoda, William S Talbot

Research output: Contribution to journalArticlepeer-review

Abstract

Myelinated axons are essential for rapid conduction of action potentials in the vertebrate nervous system. Of particular importance are the nodes of Ranvier, sites of voltage-gated sodium channel clustering that allow action potentials to be propagated along myelinated axons by saltatory conduction. Despite their critical role in the function of myelinated axons, little is known about the mechanisms that organize the nodes of Ranvier.
Original languageEnglish
Pages (from-to)636-48
Number of pages13
JournalCurrent biology : CB
Volume16
Issue number7
DOIs
Publication statusPublished - 2006

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