nsf is essential for organization of myelinated axons in zebrafish

Ian G Woods; David A Lyons; Matthew G Voas; Hans-Martin Pogoda; William S Talbot

doi:10.1016/j.cub.2006.02.067

nsf is essential for organization of myelinated axons in zebrafish

Ian G Woods, David A Lyons, Matthew G Voas, Hans-Martin Pogoda, William S Talbot

Deanery of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Myelinated axons are essential for rapid conduction of action potentials in the vertebrate nervous system. Of particular importance are the nodes of Ranvier, sites of voltage-gated sodium channel clustering that allow action potentials to be propagated along myelinated axons by saltatory conduction. Despite their critical role in the function of myelinated axons, little is known about the mechanisms that organize the nodes of Ranvier.

Original language	English
Pages (from-to)	636-48
Number of pages	13
Journal	Current biology : CB
Volume	16
Issue number	7
DOIs	https://doi.org/10.1016/j.cub.2006.02.067
Publication status	Published - 2006

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title = "nsf is essential for organization of myelinated axons in zebrafish",

abstract = "Myelinated axons are essential for rapid conduction of action potentials in the vertebrate nervous system. Of particular importance are the nodes of Ranvier, sites of voltage-gated sodium channel clustering that allow action potentials to be propagated along myelinated axons by saltatory conduction. Despite their critical role in the function of myelinated axons, little is known about the mechanisms that organize the nodes of Ranvier.",

author = "Woods, {Ian G} and Lyons, {David A} and Voas, {Matthew G} and Hans-Martin Pogoda and Talbot, {William S}",

year = "2006",

doi = "10.1016/j.cub.2006.02.067",

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T1 - nsf is essential for organization of myelinated axons in zebrafish

AU - Woods, Ian G

AU - Lyons, David A

AU - Voas, Matthew G

AU - Pogoda, Hans-Martin

AU - Talbot, William S

PY - 2006

Y1 - 2006

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AB - Myelinated axons are essential for rapid conduction of action potentials in the vertebrate nervous system. Of particular importance are the nodes of Ranvier, sites of voltage-gated sodium channel clustering that allow action potentials to be propagated along myelinated axons by saltatory conduction. Despite their critical role in the function of myelinated axons, little is known about the mechanisms that organize the nodes of Ranvier.

U2 - 10.1016/j.cub.2006.02.067

DO - 10.1016/j.cub.2006.02.067

M3 - Article

C2 - 16581508

VL - 16

SP - 636

EP - 648

JO - Current Biology

JF - Current Biology

SN - 0960-9822

IS - 7

ER -