Nucleotide sequence of a highly conserved region of the canine p53 tumour suppressor gene

L Nasir, D J Argyle, S T McFarlane, S W Reid

Research output: Contribution to journalArticlepeer-review

Abstract

An evolutionary conserved region of the canine tumour suppressor gene, p53, was PCR amplified and its DNA sequence determined. The 1003 bp fragment consisted of exons 5 to 8 and the intervening introns. A high level of sequence homology was demonstrated with human sequences, with the evolutionary conserved domains II, III, IV and V being identical.
Original languageEnglish
Pages (from-to)83-6
Number of pages4
JournalDNA Sequence
Volume8
Issue number1-2
Publication statusPublished - 1997

Keywords

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Conserved Sequence
  • Dogs
  • Exons
  • Genes, p53
  • Humans
  • Molecular Sequence Data
  • Sequence Analysis, DNA
  • Sequence Homology, Nucleic Acid

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