Nucleotide sequence of a highly conserved region of the canine p53 tumour suppressor gene

L Nasir; D J Argyle; S T McFarlane; S W Reid

Nucleotide sequence of a highly conserved region of the canine p53 tumour suppressor gene

L Nasir, D J Argyle, S T McFarlane, S W Reid

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

An evolutionary conserved region of the canine tumour suppressor gene, p53, was PCR amplified and its DNA sequence determined. The 1003 bp fragment consisted of exons 5 to 8 and the intervening introns. A high level of sequence homology was demonstrated with human sequences, with the evolutionary conserved domains II, III, IV and V being identical.

Original language	English
Pages (from-to)	83-6
Number of pages	4
Journal	DNA Sequence
Volume	8
Issue number	1-2
Publication status	Published - 1997

Keywords / Materials (for Non-textual outputs)

Amino Acid Sequence
Animals
Base Sequence
Conserved Sequence
Dogs
Exons
Genes, p53
Humans
Molecular Sequence Data
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid

Cite this

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title = "Nucleotide sequence of a highly conserved region of the canine p53 tumour suppressor gene",

abstract = "An evolutionary conserved region of the canine tumour suppressor gene, p53, was PCR amplified and its DNA sequence determined. The 1003 bp fragment consisted of exons 5 to 8 and the intervening introns. A high level of sequence homology was demonstrated with human sequences, with the evolutionary conserved domains II, III, IV and V being identical.",

keywords = "Amino Acid Sequence, Animals, Base Sequence, Conserved Sequence, Dogs, Exons, Genes, p53, Humans, Molecular Sequence Data, Sequence Analysis, DNA, Sequence Homology, Nucleic Acid",

author = "L Nasir and Argyle, {D J} and McFarlane, {S T} and Reid, {S W}",

year = "1997",

language = "English",

volume = "8",

pages = "83--6",

journal = "DNA Sequence",

issn = "1042-5179",

publisher = "Taylor & Francis",

number = "1-2",

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TY - JOUR

T1 - Nucleotide sequence of a highly conserved region of the canine p53 tumour suppressor gene

AU - Nasir, L

AU - Argyle, D J

AU - McFarlane, S T

AU - Reid, S W

PY - 1997

Y1 - 1997

N2 - An evolutionary conserved region of the canine tumour suppressor gene, p53, was PCR amplified and its DNA sequence determined. The 1003 bp fragment consisted of exons 5 to 8 and the intervening introns. A high level of sequence homology was demonstrated with human sequences, with the evolutionary conserved domains II, III, IV and V being identical.

AB - An evolutionary conserved region of the canine tumour suppressor gene, p53, was PCR amplified and its DNA sequence determined. The 1003 bp fragment consisted of exons 5 to 8 and the intervening introns. A high level of sequence homology was demonstrated with human sequences, with the evolutionary conserved domains II, III, IV and V being identical.

KW - Amino Acid Sequence

KW - Animals

KW - Base Sequence

KW - Conserved Sequence

KW - Dogs

KW - Exons

KW - Genes, p53

KW - Humans

KW - Molecular Sequence Data

KW - Sequence Analysis, DNA

KW - Sequence Homology, Nucleic Acid

M3 - Article

C2 - 9522126

SN - 1042-5179

VL - 8

SP - 83

EP - 86

JO - DNA Sequence

JF - DNA Sequence

IS - 1-2

ER -

Nucleotide sequence of a highly conserved region of the canine p53 tumour suppressor gene

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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Cite this