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Abstract / Description of output
The formation of pairs of particles or cells of different types in microfluidic channels can be desired or detrimental in healthcare applications. It is still unclear what role softness heterogeneity plays in the formation of these particle pairs. We use an in-house lattice-Boltzmann–immersed-boundary–finite-element solver to simulate a pair of particles with different softness flowing through a straight channel with a rectangular cross-section under initial conditions representative of a dilute suspension. We find that softness heterogeneity significantly affects the pair dynamics, determining whether a pair will form or not, and determining the lateral and inter-particle equilibrium behaviour in the pair. We also observe close matches between the transient deformation of particles in a linear pair and single particles in isolation. These results further our understanding of pair behaviour, providing a foundation for understanding particle train formation, and open up the potential to develop reduced-order models for particle pair formation based upon the behaviour of single particles.
Original language | English |
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Journal | Soft Matter |
Early online date | 23 Dec 2023 |
DOIs | |
Publication status | E-pub ahead of print - 23 Dec 2023 |
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Dive into the research topics of 'Numerical investigation of heterogeneous soft particle pairs in inertial microfluidics'. Together they form a unique fingerprint.Projects
- 1 Finished
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Lattice-Boltzmann Modelling for Inertial Particle Microfluidics Applications — A Tutorial Review
Owen, B., Kechagidis, K., Razavi Bazaz, S., Enjalbert, R., Essmann, E., Mallorie, C., Mirghaderi, F., Schaaf, C., Thota, K., Vernekar, R., Zhou, Q., Ebrahimi Warkiani, M., Stark, H. & Krüger, T., 24 Sept 2023, (E-pub ahead of print) In: Advances in Physics X. 8, 1, 2246704.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Numerical study of the formation and stability of a pair of particles of different sizes in inertial microfluidics
Thota, K., Owen, B. & Krüger, T., Mar 2023, In: Physics of Fluids. 35, 3, 032001.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Numerical investigation of the formation and stability of homogeneous pairs of soft particles in inertial microfluidics
Owen, B. & Krüger, T., 25 Apr 2022, In: Journal of Fluid Mechanics. 937, 31 p., A4.Research output: Contribution to journal › Article › peer-review
Open Access