Objective quantification of muscle and fat in human dystrophic muscle by magnetic resonance image analysis

J Phoenix; D Betal; N Roberts; TR Helliwell; RHT Edwards

Objective quantification of muscle and fat in human dystrophic muscle by magnetic resonance image analysis

J Phoenix, D Betal, N Roberts, TR Helliwell, RHT Edwards

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Information about changes in muscle composition has to date been primarily restricted to histological examination of biopsy samples or qualitative assessment of images obtained using a variety of techniques (e.g., ultrasound, CT, and MRI). We describe the development of a quantitative method far the analysis of muscle composition using MR T-2 relaxation time mapping and image analysis. This approach provides an objective means of studying muscle and, when used in conjunction with force production measurements, may provide an accurate measure of response to muscle therapy. (C) 1996 John Wiley & Sons, Inc.

Original language	English
Pages (from-to)	302-310
Number of pages	9
Journal	Muscle & Nerve
Volume	19
Issue number	3
Publication status	Published - Mar 1996

Keywords / Materials (for Non-textual outputs)

DUCHENNE MUSCULAR-DYSTROPHY
CROSS-SECTIONAL AREA
SKELETAL-MUSCLE
DISEASED MUSCLE
ULTRASOUND
STRENGTH
TRANSPLANTATION
TOMOGRAPHY
CHILDREN
TISSUE

Cite this

@article{f9f46370b14142a286d10b9c737fc67c,

title = "Objective quantification of muscle and fat in human dystrophic muscle by magnetic resonance image analysis",

abstract = "Information about changes in muscle composition has to date been primarily restricted to histological examination of biopsy samples or qualitative assessment of images obtained using a variety of techniques (e.g., ultrasound, CT, and MRI). We describe the development of a quantitative method far the analysis of muscle composition using MR T-2 relaxation time mapping and image analysis. This approach provides an objective means of studying muscle and, when used in conjunction with force production measurements, may provide an accurate measure of response to muscle therapy. (C) 1996 John Wiley & Sons, Inc.",

keywords = "DUCHENNE MUSCULAR-DYSTROPHY, CROSS-SECTIONAL AREA, SKELETAL-MUSCLE, DISEASED MUSCLE, ULTRASOUND, STRENGTH, TRANSPLANTATION, TOMOGRAPHY, CHILDREN, TISSUE",

author = "J Phoenix and D Betal and N Roberts and TR Helliwell and RHT Edwards",

year = "1996",

month = mar,

language = "English",

volume = "19",

pages = "302--310",

journal = "Muscle & Nerve",

issn = "0148-639X",

publisher = "John Wiley & Sons Inc.",

number = "3",

}

TY - JOUR

T1 - Objective quantification of muscle and fat in human dystrophic muscle by magnetic resonance image analysis

AU - Phoenix, J

AU - Betal, D

AU - Roberts, N

AU - Helliwell, TR

AU - Edwards, RHT

PY - 1996/3

Y1 - 1996/3

N2 - Information about changes in muscle composition has to date been primarily restricted to histological examination of biopsy samples or qualitative assessment of images obtained using a variety of techniques (e.g., ultrasound, CT, and MRI). We describe the development of a quantitative method far the analysis of muscle composition using MR T-2 relaxation time mapping and image analysis. This approach provides an objective means of studying muscle and, when used in conjunction with force production measurements, may provide an accurate measure of response to muscle therapy. (C) 1996 John Wiley & Sons, Inc.

AB - Information about changes in muscle composition has to date been primarily restricted to histological examination of biopsy samples or qualitative assessment of images obtained using a variety of techniques (e.g., ultrasound, CT, and MRI). We describe the development of a quantitative method far the analysis of muscle composition using MR T-2 relaxation time mapping and image analysis. This approach provides an objective means of studying muscle and, when used in conjunction with force production measurements, may provide an accurate measure of response to muscle therapy. (C) 1996 John Wiley & Sons, Inc.

KW - DUCHENNE MUSCULAR-DYSTROPHY

KW - CROSS-SECTIONAL AREA

KW - SKELETAL-MUSCLE

KW - DISEASED MUSCLE

KW - ULTRASOUND

KW - STRENGTH

KW - TRANSPLANTATION

KW - TOMOGRAPHY

KW - CHILDREN

KW - TISSUE

M3 - Article

SN - 0148-639X

VL - 19

SP - 302

EP - 310

JO - Muscle & Nerve

JF - Muscle & Nerve

IS - 3

ER -

Objective quantification of muscle and fat in human dystrophic muscle by magnetic resonance image analysis

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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