Oligodendrocyte dysfunction in schizophrenia and bipolar disorder

Dmitri Tkachev, Michael L Mimmack, Margaret M Ryan, Matt Wayland, Tom Freeman, Peter B Jones, Michael Starkey, Maree J Webster, Robert H Yolken, Sabine Bahn

Research output: Contribution to journalArticlepeer-review

Abstract

Results of array studies have suggested abnormalities in expression of lipid and myelin-related genes in schizophrenia. Here, we investigated oligodendrocyte-specific and myelination-associated gene expression in schizophrenia and bipolar affective disorder.
Original languageEnglish
Pages (from-to)798-805
Number of pages8
JournalThe Lancet
Volume362
Issue number9386
DOIs
Publication statusPublished - 6 Sep 2003

Keywords

  • Bipolar Disorder
  • Brain
  • Brain Chemistry
  • Down-Regulation
  • Gene Expression Profiling
  • Gene Expression Regulation
  • Humans
  • Myelin Proteins
  • Myelin Sheath
  • Myelin-Associated Glycoprotein
  • Myelin-Oligodendrocyte Glycoprotein
  • Oligodendroglia
  • Oligonucleotide Array Sequence Analysis
  • Polymerase Chain Reaction
  • Schizophrenia

Fingerprint Dive into the research topics of 'Oligodendrocyte dysfunction in schizophrenia and bipolar disorder'. Together they form a unique fingerprint.

Cite this