Projects per year
We performed a prospective, observational, cohort study of children newly diagnosed with children’s interstitial lung disease (ChILD), with structured follow-up at 4, 8, 12 weeks and 6 and 12 months. 127 children, median age 0.9 (IQR 0.3–7.9) years had dyspnoea (68%, 69/102), tachypnoea (75%, 77/103) and low oxygen saturation (SpO2) median 92% (IQR 88–96). Death (n=20, 16%) was the most common in those <6 months of age with SpO2<94% and developmental/surfactant disorders. We report for the first time that ChILD survivors improved multiple clinical parameters within 8–12 weeks of diagnosis. These data can inform family discussions and support clinical trial measurements.
|Early online date||20 Nov 2019|
|Publication status||Published - Feb 2020|
FingerprintDive into the research topics of 'One-year outcomes in a multicentre cohort study of incident rare diffuse parenchymal lung disease in children (ChILD)'. Together they form a unique fingerprint.
- 1 Finished
Orphans Unite: chILD better together European Management Platform for Childhood Interstitial Lung Diseases
1/12/12 → 30/11/16
- Deanery of Clinical Sciences - Professor of Paediatric Respiratory Medicine
- MRC Centre for Reproductive Health
- Centre for Inflammation Research
Person: Academic: Research Active