Optical detection in microfluidics: From the small to the large

Andrew J. DeMello, P. M.W. French, M. A.A. Neil, J. B. Edel, R. K.P. Benninger, D. D.C. Bradley, T. Robinson, M. Srisa-art, O. Hofmann, J. C. DeMello

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Herein we discuss two broad approaches for performing high sensitivity optical detection within microfluidic environments. First, we describe recent work in which fluorescence lifetime imaging has been shown to be a sensitive probe of environmental parameters such as pH, viscosity, molecular concentration and temperature. Additionally, we demonstrate how dynamic fluorescence lifetime imaging can be used to probe mixing dynamics in segmented-flow microfluidic systems. Moreover, we describe recent work at Imperial College London in which semiconducting polymer light emitting diodes and polymer photodetectors are integrated with microfluidic systems to define a novel format for point-of-care diagnostics.

Original languageEnglish
Title of host publicationTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
Pages712-717
Number of pages6
DOIs
Publication statusPublished - 13 Oct 2009
EventTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems - Denver, CO, United States
Duration: 21 Jun 200925 Jun 2009

Publication series

NameTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems

Conference

ConferenceTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
Country/TerritoryUnited States
CityDenver, CO
Period21/06/0925/06/09

Keywords / Materials (for Non-textual outputs)

  • Fluorescence lifetime imaging
  • Microfluidics
  • Point-of-care diagnostics
  • Polymer light emitting diodes

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