Organic dust exposure increases mast cell tryptase in bronchoalveolar lavage fluid and airway epithelium of heaves horses

K J Dacre, B C McGorum, D J Marlin, L R Bartner, J K Brown, D J Shaw, N E Robinson, C Deaton, A D Pemberton

Research output: Contribution to journalArticlepeer-review

Abstract

Mast cell degranulation is believed to act as a key event in initiating and maintaining airway response to allergen challenge in human asthma. It is hypothesized that the mast cell may play a similar role in equine heaves, which shares many similarities with occupational dust-induced asthma.
Original languageEnglish
Pages (from-to)1809-18
Number of pages10
JournalClinical and Experimental Allergy
Volume37
Issue number12
DOIs
Publication statusPublished - 2007

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