Organometallic generation and capture of ortho-arynes

Alan M. Dyke, Alison J. Hester, Guy C. Lloyd-Jones*

*Corresponding author for this work

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

This literature review focuses on the use of metal- or metalloid-based reagents to generate ortho-arynes from stable precursors via organometallic intermediates or to generate organometallic complexes of ortho-arynes. The review also encompasses the capture of arynes by organometallics to generate new complexes, with interesting reactivity in their own right, or as intermediates in catalytic systems. The purpose of the review is to highlight the novelty, utility and versatility of the interaction of orgariometallic species with arynes and their precursors. These points are illustrated through a number of examples of the application of such methods in the preparation of complex organic molecules. The review contains some 197 references and covers the literature up to May 2006.

Original languageEnglish
Pages (from-to)4093-4112
Number of pages20
JournalSynthesis: Journal of Synthetic Organic Chemistry
Issue number24
DOIs
Publication statusPublished - 18 Dec 2006

Keywords

  • arynes
  • organometallic reagents
  • catalysis
  • main group metals
  • transition metals
  • BENZYNE-FURAN CYCLOADDITION
  • TANDEM ADDITION-REARRANGEMENT
  • THIA-FRIES REARRANGEMENT
  • HIGHLY EFFICIENT ROUTE
  • DIELS-ALDER REACTIONS
  • KETENE SILYL ACETAL
  • ONE-POT SYNTHESIS
  • GAS-PHASE
  • STRAIGHTFORWARD SYNTHESIS
  • ZIRCONOCENE COMPLEXES

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