Outbreak of acute hepatitis C following the use of anti-hepatitis C virus--screened intravenous immunoglobulin therapy

C J Healey; N K Sabharwal; J Daub; F Davidson; P L Yap; K A Fleming; R W Chapman; P Simmonds; H Chapel

doi:10.1053/gast.1996.v110.pm8613001

Outbreak of acute hepatitis C following the use of anti-hepatitis C virus--screened intravenous immunoglobulin therapy

C J Healey, N K Sabharwal, J Daub, F Davidson, P L Yap, K A Fleming, R W Chapman, P Simmonds, H Chapel

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

Hepatitis C virus (HCV) infection has been associated with intravenous (IV) immunoglobulin (Ig), and plasma donations used to prepare IV Ig are now screened to prevent transmission. Thirty-six patients from the United Kingdom received infusions from a batch of anti-HCV antibody-screened intravenous Ig (Gammagard; Baxter Healthcare Ltd., Thetford, Norfolk, England) that was associated with reports of acute hepatitis C outbreak in Europe. The aim of this study was to document the epidemiology of this outbreak.

Original language	English
Pages (from-to)	1120-6
Number of pages	7
Journal	Gastroenterology
Volume	110
Issue number	4
DOIs	https://doi.org/10.1053/gast.1996.v110.pm8613001
Publication status	Published - Apr 1996

Keywords

Acute Disease
Adolescent
Adult
Aged
Child
Disease Outbreaks
Female
Follow-Up Studies
Genotype
Great Britain
Hepacivirus
Hepatitis C
Hepatitis C Antibodies
Humans
Immunoglobulins, Intravenous
Male
Middle Aged
Polymerase Chain Reaction
RNA, Viral

Access to Document

10.1053/gast.1996.v110.pm8613001

Outbreak of acute hepatitis C following the use of anti-hepatitis C virus--screened intravenous immunoglobulin therapy
Copyright 1996 by the American Gastroenterological Association
Final published version, 103 KB

Cite this

@article{b862decfcdd94a77adfdbdbbc8637261,

title = "Outbreak of acute hepatitis C following the use of anti-hepatitis C virus--screened intravenous immunoglobulin therapy",

abstract = "Hepatitis C virus (HCV) infection has been associated with intravenous (IV) immunoglobulin (Ig), and plasma donations used to prepare IV Ig are now screened to prevent transmission. Thirty-six patients from the United Kingdom received infusions from a batch of anti-HCV antibody-screened intravenous Ig (Gammagard; Baxter Healthcare Ltd., Thetford, Norfolk, England) that was associated with reports of acute hepatitis C outbreak in Europe. The aim of this study was to document the epidemiology of this outbreak.",

keywords = "Acute Disease, Adolescent, Adult, Aged, Child, Disease Outbreaks, Female, Follow-Up Studies, Genotype, Great Britain, Hepacivirus, Hepatitis C, Hepatitis C Antibodies, Humans, Immunoglobulins, Intravenous, Male, Middle Aged, Polymerase Chain Reaction, RNA, Viral",

author = "Healey, {C J} and Sabharwal, {N K} and J Daub and F Davidson and Yap, {P L} and Fleming, {K A} and Chapman, {R W} and P Simmonds and H Chapel",

year = "1996",

month = apr,

doi = "10.1053/gast.1996.v110.pm8613001",

language = "English",

volume = "110",

pages = "1120--6",

journal = "Gastroenterology",

issn = "1528-0012",

publisher = "W.B. Saunders Ltd",

number = "4",

}

TY - JOUR

T1 - Outbreak of acute hepatitis C following the use of anti-hepatitis C virus--screened intravenous immunoglobulin therapy

AU - Healey, C J

AU - Sabharwal, N K

AU - Daub, J

AU - Davidson, F

AU - Yap, P L

AU - Fleming, K A

AU - Chapman, R W

AU - Simmonds, P

AU - Chapel, H

PY - 1996/4

Y1 - 1996/4

N2 - Hepatitis C virus (HCV) infection has been associated with intravenous (IV) immunoglobulin (Ig), and plasma donations used to prepare IV Ig are now screened to prevent transmission. Thirty-six patients from the United Kingdom received infusions from a batch of anti-HCV antibody-screened intravenous Ig (Gammagard; Baxter Healthcare Ltd., Thetford, Norfolk, England) that was associated with reports of acute hepatitis C outbreak in Europe. The aim of this study was to document the epidemiology of this outbreak.

AB - Hepatitis C virus (HCV) infection has been associated with intravenous (IV) immunoglobulin (Ig), and plasma donations used to prepare IV Ig are now screened to prevent transmission. Thirty-six patients from the United Kingdom received infusions from a batch of anti-HCV antibody-screened intravenous Ig (Gammagard; Baxter Healthcare Ltd., Thetford, Norfolk, England) that was associated with reports of acute hepatitis C outbreak in Europe. The aim of this study was to document the epidemiology of this outbreak.

KW - Acute Disease

KW - Adolescent

KW - Adult

KW - Aged

KW - Child

KW - Disease Outbreaks

KW - Female

KW - Follow-Up Studies

KW - Genotype

KW - Great Britain

KW - Hepacivirus

KW - Hepatitis C

KW - Hepatitis C Antibodies

KW - Humans

KW - Immunoglobulins, Intravenous

KW - Male

KW - Middle Aged

KW - Polymerase Chain Reaction

KW - RNA, Viral

U2 - 10.1053/gast.1996.v110.pm8613001

DO - 10.1053/gast.1996.v110.pm8613001

M3 - Article

C2 - 8613001

VL - 110

SP - 1120

EP - 1126

JO - Gastroenterology

JF - Gastroenterology

SN - 1528-0012

IS - 4

ER -

Outbreak of acute hepatitis C following the use of anti-hepatitis C virus--screened intravenous immunoglobulin therapy

Abstract

Keywords

Access to Document

Fingerprint

Cite this