Overdose pattern and outcome in paracetamol-induced acute severe hepatotoxicity

Darren G N Craig; Caroline M Bates; Janice S Davidson; Kirsty G Martin; Peter C Hayes; Kenneth J Simpson

doi:10.1111/j.1365-2125.2010.03819.x

Overdose pattern and outcome in paracetamol-induced acute severe hepatotoxicity

Darren G N Craig, Caroline M Bates, Janice S Davidson, Kirsty G Martin, Peter C Hayes, Kenneth J Simpson

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Paracetamol (acetaminophen) hepatotoxicity is the commonest cause of acute liver failure (ALF) in the UK. Conflicting data regarding the outcomes of paracetamol-induced ALF resulting from different overdose patterns are reported.

Original language	English
Pages (from-to)	273-82
Number of pages	10
Journal	British Journal of Clinical Pharmacology
Volume	71
Issue number	2
DOIs	https://doi.org/10.1111/j.1365-2125.2010.03819.x
Publication status	Published - Feb 2011

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title = "Overdose pattern and outcome in paracetamol-induced acute severe hepatotoxicity",

abstract = "Paracetamol (acetaminophen) hepatotoxicity is the commonest cause of acute liver failure (ALF) in the UK. Conflicting data regarding the outcomes of paracetamol-induced ALF resulting from different overdose patterns are reported.",

author = "Craig, {Darren G N} and Bates, {Caroline M} and Davidson, {Janice S} and Martin, {Kirsty G} and Hayes, {Peter C} and Simpson, {Kenneth J}",

note = "{\textcopyright} 2011 The Authors. British Journal of Clinical Pharmacology {\textcopyright} 2011 The British Pharmacological Society.",

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AU - Hayes, Peter C

AU - Simpson, Kenneth J

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DO - 10.1111/j.1365-2125.2010.03819.x

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JO - British Journal of Clinical Pharmacology

JF - British Journal of Clinical Pharmacology

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Overdose pattern and outcome in paracetamol-induced acute severe hepatotoxicity

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