Abstract
Cardiovascular causes have been estimated to be responsible for more than two thirds of the considerable mortality attributed to air pollution. There is now a substantial body of research demonstrating that exposure to air pollution has many detrimental effects throughout the cardiovascular system. Multiple biological mechanisms are responsible, however, oxidative stress is a prominent observation at many levels of the cardiovascular impairment induced by pollutant exposure. This review provides an overview of the evidence that oxidative stress is a key pathway for the different cardiovascular actions of air pollution.
Original language | English |
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Journal | Free Radical Biology and Medicine |
Early online date | 7 Jan 2020 |
DOIs | |
Publication status | E-pub ahead of print - 7 Jan 2020 |