Oxidative stress and the cardiovascular effects of air pollution

Mark R Miller

doi:10.1016/j.freeradbiomed.2020.01.004

Oxidative stress and the cardiovascular effects of air pollution

Research output: Contribution to journal › Review article › peer-review

Abstract / Description of output

Cardiovascular causes have been estimated to be responsible for more than two thirds of the considerable mortality attributed to air pollution. There is now a substantial body of research demonstrating that exposure to air pollution has many detrimental effects throughout the cardiovascular system. Multiple biological mechanisms are responsible, however, oxidative stress is a prominent observation at many levels of the cardiovascular impairment induced by pollutant exposure. This review provides an overview of the evidence that oxidative stress is a key pathway for the different cardiovascular actions of air pollution.

Original language	English
Journal	Free Radical Biology and Medicine
Early online date	7 Jan 2020
DOIs	https://doi.org/10.1016/j.freeradbiomed.2020.01.004
Publication status	E-pub ahead of print - 7 Jan 2020

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10.1016/j.freeradbiomed.2020.01.004

1-s2.0-S0891584919322750-mainProof, 3.92 MBLicence: CC BY

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title = "Oxidative stress and the cardiovascular effects of air pollution",

abstract = "Cardiovascular causes have been estimated to be responsible for more than two thirds of the considerable mortality attributed to air pollution. There is now a substantial body of research demonstrating that exposure to air pollution has many detrimental effects throughout the cardiovascular system. Multiple biological mechanisms are responsible, however, oxidative stress is a prominent observation at many levels of the cardiovascular impairment induced by pollutant exposure. This review provides an overview of the evidence that oxidative stress is a key pathway for the different cardiovascular actions of air pollution.",

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AB - Cardiovascular causes have been estimated to be responsible for more than two thirds of the considerable mortality attributed to air pollution. There is now a substantial body of research demonstrating that exposure to air pollution has many detrimental effects throughout the cardiovascular system. Multiple biological mechanisms are responsible, however, oxidative stress is a prominent observation at many levels of the cardiovascular impairment induced by pollutant exposure. This review provides an overview of the evidence that oxidative stress is a key pathway for the different cardiovascular actions of air pollution.

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DO - 10.1016/j.freeradbiomed.2020.01.004

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SN - 0891-5849

JO - Free Radical Biology and Medicine

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Oxidative stress and the cardiovascular effects of air pollution

Abstract / Description of output

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