Oxidative stress and the cardiovascular effects of air pollution

Research output: Contribution to journalReview articlepeer-review

Abstract

Cardiovascular causes have been estimated to be responsible for more than two thirds of the considerable mortality attributed to air pollution. There is now a substantial body of research demonstrating that exposure to air pollution has many detrimental effects throughout the cardiovascular system. Multiple biological mechanisms are responsible, however, oxidative stress is a prominent observation at many levels of the cardiovascular impairment induced by pollutant exposure. This review provides an overview of the evidence that oxidative stress is a key pathway for the different cardiovascular actions of air pollution.

Original languageEnglish
JournalFree Radical Biology and Medicine
Early online date7 Jan 2020
DOIs
Publication statusE-pub ahead of print - 7 Jan 2020

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