TY - JOUR
T1 - Paranasal sinuses opacification on magnetic resonance imaging in relation to brain health in sporadic small vessel disease – Systematic review and pilot analysis
AU - Sáenz de Villaverde Cortabarría, Alba
AU - Zhang, Jun-fang
AU - Valdés Hernández, Maria C
AU - Wu, Yun-cheng
AU - Clancy, Una
AU - Sakka, Eleni
AU - Ferguson, Karen
AU - Wiseman, Stewart
AU - Hewins, Will
AU - Jaime Garcia, Dany
AU - Stringer, Michael
AU - Thrippleton, Michael J
AU - Chappell, Francesca M
AU - Doubal, Fergus
AU - Wu, Yun-cheng
AU - Wardlaw, Joanna M.
AU - the Mild Stroke Study 3 (MSS3) study group
N1 - Funding Information:
This work has been supported by The Row Fogo Charitable Trust Centre for Research into Aging and the Brain (BRO-D.FID3668413); The Galen and Hilary Weston Foundation under the Novel Biomarkers 2019 scheme (ref UB190097) administered by the Weston Brain Institute ; the UK Dementia Research Institute which receives its funding from DRI Ltd., funded by the UK MRC, Alzheimer's Society and Alzheimer's Research UK ; the Fondation Leducq Network for the Study of Perivascular Spaces in Small Vessel Disease (16 CVD 05); Stroke Association ‘Small Vessel Disease-Spotlight on Symptoms (SVD-SOS)’ (SAPG 19\100068); British Heart Foundation Edinburgh Centre for Research Excellence (RE/18/5/34216); NHS Lothian Research and Development Office (MJT) ; Stroke Association Post-Doctoral Fellowship (SJW) (SAPDF 18/ 100026); Chief Scientist Office of Scotland Clinical Academic Fellowship (UC) (CAF/18/08); Stroke Association Princess Margaret Research Development Fellowship (UC) (2018); Ministry of Science and Technology of the People's Republic of China (STI2030-Major Projects2021ZD0201900, 2021ZD0201905); National Natural Science Foundation of China (81971185, 82171243) Science and Technology Innovation 2030-“Brain Science and Brain-Like Intelligence Technology” Major Project ( The China Brain Project ) (No. 2021ZD0201905); Major Project of Scientific and Technological Innovation Action Plan of Shanghai Science and Technology Commission (21Y31920300, 21Y31920304); and the Clinical Research Innovation Plan of Shanghai General Hospital (CCTR-2022B07). The research MRI scanner is supported by the Scottish Funding Council through the Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration; the Wellcome Trust (104916/Z/14/Z), Dunhill Trust (R380R/1114), Edinburgh and Lothians Health Foundation (2012/17), Muir Maxwell Research Fund and the University of Edinburgh.
Publisher Copyright:
© 2023 Elsevier B.V.
PY - 2023/7/17
Y1 - 2023/7/17
N2 - The paranasal sinus mucosal thickening, visible in magnetic resonance imaging (MRI), maybe a source of inflammation in microvessels, but its relationship with small vessel disease (SVD) is unclear. We reviewed the literature and analysed a sample of patients with sporadic SVD to identify any association between paranasal sinus opacification severity and SVD neuroimaging markers.
AB - The paranasal sinus mucosal thickening, visible in magnetic resonance imaging (MRI), maybe a source of inflammation in microvessels, but its relationship with small vessel disease (SVD) is unclear. We reviewed the literature and analysed a sample of patients with sporadic SVD to identify any association between paranasal sinus opacification severity and SVD neuroimaging markers.
U2 - 10.1016/j.jns.2023.120735
DO - 10.1016/j.jns.2023.120735
M3 - Article
SN - 0022-510X
JO - Journal of the Neurological Sciences
JF - Journal of the Neurological Sciences
ER -