Parental causes of death in stroke

J Starr, M Rush, R De Mey, M Dennis

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

There are many reports of familial aggregation in stroke. However, whether familial aggregation is largely due to genetic or environmental factors is not established. Consecutive subjects with stroke were matched with 2 controls per case of the same sex, born in the same year, district, and whose fathers had the same occupation. Presence on parental death certificates of cerebrovascular disease, other vascular disease, bronchial carcinoma, hypertension, diabetes mellitus and other causes of death was recorded. No significant difference in risk was found for cases having mother (odds ratio, OR 1.08, 95% confidence interval, CI, 0.74-1.57), father (OR 0.91, 95% CI 0.58-1.45) or either parent (OR 1.04, 95% CI 0.74-1.46) with cerebrovascular disease. Familial aggregation may reflect socioeconomic and other environmental factors.

Original languageEnglish
Pages (from-to)65-70
Number of pages6
JournalCerebrovascular diseases (Basel, Switzerland)
Volume11
Issue number1
DOIs
Publication statusPublished - 2001

Keywords / Materials (for Non-textual outputs)

  • Adult
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Cause of Death
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mothers
  • Parents
  • Risk Factors
  • Stroke

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