Patches in the livers of chimaeric mice

J D West

Research output: Contribution to journalArticlepeer-review


Sections of adult chimaeric livers have been histochemically stained for beta-glucuronidase activity and patches of two cell populations visualized. A one-dimensional clonal analysis has been used to estimate the number of coherent clones in the adult liver. The data are consistent with a total of 9-22 million regular, coherent clones, comprising 10-34 nuclei, or a smaller number of irregular, branched coherent clones. Both of these alternatives suggest considerable cell mixing during liver morphogenesis.

Original languageEnglish
Pages (from-to)151-61
Number of pages11
JournalJournal of embryology and experimental morphology
Issue number1
Publication statusPublished - Aug 1976


  • Animals
  • Cell Aggregation
  • Cell Count
  • Cell Movement
  • Cell Nucleus
  • Chimera
  • Clone Cells
  • Glucuronidase
  • Liver
  • Mice
  • Mice, Inbred C3H
  • Mice, Inbred C57BL
  • Mosaicism
  • Organ Size


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