Pathogenicity islands and virulence evolution in Listeria

Jose A Vazquez-Boland, Gustavo Dominguez-Bernal, Bruno González Zörn, Jurgen Kreft, Werner Goebel

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

As in other bacterial pathogens, the virulence determinants of Listeria species are clustered in genomic islands scattered along the chromosome. This review summarizes current knowledge about the structure, distribution and role in pathogenesis of Listeria virulence loci. Hypotheses about the mode of acquisition and evolution of these loci in this group of Gram-positive bacteria are presented and discussed.
Original languageEnglish
Pages (from-to)571-84
Number of pages14
JournalMicrobes and Infection
Volume3
Issue number7
DOIs
Publication statusPublished - Jun 2001

Keywords

  • Amino Acid Sequence
  • Animals
  • Bacterial Proteins/classification
  • Bacterial Proteins/genetics
  • Bacterial Proteins/physiology
  • Chromosomes, Bacterial/genetics
  • Evolution, Molecular
  • Humans
  • Listeria/genetics
  • Listeria/pathogenicity
  • Listeriosis/microbiology
  • Molecular Sequence Data
  • Multigene Family
  • Virulence/genetics

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