Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica

P Piccardo; M Ceroni; P Rodgers-Johnson; C Mora; D M Asher; G Char; C J Gibbs; D C Gajdusek

Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica

P Piccardo, M Ceroni, P Rodgers-Johnson, C Mora, D M Asher, G Char, C J Gibbs, D C Gajdusek

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

The neuropathological examination of the spinal cord of 2 Jamaican patients with classical tropical spastic paraparesis disclosed an intense chronic meningomyelitis with demyelination. In the 1 case in which serum and cerebrospinal fluid were available, antibodies to the human T-lymphotropic virus type 1 were found.

Original language	English
Pages (from-to)	S156-60
Journal	Annals of Neurology
Volume	23 Suppl
Publication status	Published - 1988

Keywords

Adult
Antibodies, Anti-Idiotypic
Antibodies, Viral
Brain
Deltaretrovirus Antibodies
Female
Humans
Immunoglobulin G
Jamaica
Muscle Spasticity
Paraplegia
Spinal Cord
Tropical Medicine

Cite this

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title = "Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica",

abstract = "The neuropathological examination of the spinal cord of 2 Jamaican patients with classical tropical spastic paraparesis disclosed an intense chronic meningomyelitis with demyelination. In the 1 case in which serum and cerebrospinal fluid were available, antibodies to the human T-lymphotropic virus type 1 were found.",

keywords = "Adult, Antibodies, Anti-Idiotypic, Antibodies, Viral, Brain, Deltaretrovirus Antibodies, Female, Humans, Immunoglobulin G, Jamaica, Muscle Spasticity, Paraplegia, Spinal Cord, Tropical Medicine",

author = "P Piccardo and M Ceroni and P Rodgers-Johnson and C Mora and Asher, {D M} and G Char and Gibbs, {C J} and Gajdusek, {D C}",

year = "1988",

language = "English",

volume = "23 Suppl",

pages = "S156--60",

journal = "Annals of Neurology",

issn = "0364-5134",

publisher = "John Wiley & Sons Inc.",

}

TY - JOUR

T1 - Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica

AU - Piccardo, P

AU - Ceroni, M

AU - Rodgers-Johnson, P

AU - Mora, C

AU - Asher, D M

AU - Char, G

AU - Gibbs, C J

AU - Gajdusek, D C

PY - 1988

Y1 - 1988

N2 - The neuropathological examination of the spinal cord of 2 Jamaican patients with classical tropical spastic paraparesis disclosed an intense chronic meningomyelitis with demyelination. In the 1 case in which serum and cerebrospinal fluid were available, antibodies to the human T-lymphotropic virus type 1 were found.

AB - The neuropathological examination of the spinal cord of 2 Jamaican patients with classical tropical spastic paraparesis disclosed an intense chronic meningomyelitis with demyelination. In the 1 case in which serum and cerebrospinal fluid were available, antibodies to the human T-lymphotropic virus type 1 were found.

KW - Adult

KW - Antibodies, Anti-Idiotypic

KW - Antibodies, Viral

KW - Brain

KW - Deltaretrovirus Antibodies

KW - Female

KW - Humans

KW - Immunoglobulin G

KW - Jamaica

KW - Muscle Spasticity

KW - Paraplegia

KW - Spinal Cord

KW - Tropical Medicine

M3 - Article

C2 - 2894808

VL - 23 Suppl

SP - S156-60

JO - Annals of Neurology

JF - Annals of Neurology

SN - 0364-5134

ER -

Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica

Abstract

Keywords

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