Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica

P Piccardo, M Ceroni, P Rodgers-Johnson, C Mora, D M Asher, G Char, C J Gibbs, D C Gajdusek

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The neuropathological examination of the spinal cord of 2 Jamaican patients with classical tropical spastic paraparesis disclosed an intense chronic meningomyelitis with demyelination. In the 1 case in which serum and cerebrospinal fluid were available, antibodies to the human T-lymphotropic virus type 1 were found.

Original languageEnglish
Pages (from-to)S156-60
JournalAnnals of Neurology
Volume23 Suppl
Publication statusPublished - 1988

Keywords / Materials (for Non-textual outputs)

  • Adult
  • Antibodies, Anti-Idiotypic
  • Antibodies, Viral
  • Brain
  • Deltaretrovirus Antibodies
  • Female
  • Humans
  • Immunoglobulin G
  • Jamaica
  • Muscle Spasticity
  • Paraplegia
  • Spinal Cord
  • Tropical Medicine

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