This article describes the pathology of malignant tumors of the uterine cervix, focusing particularly on the common carcinomas, squamous and adenocarcinomas, that occur at this site. Most of these tumors are associated with human papillomavirus (HPV) infection and recent developments in HPV testing and HPV vaccination are discussed. There is increasing recognition that some adenocarcinomas of the cervix are not associated with HPV infection and these, particularly gastric-type adenocarcinoma, behave aggressively. These non-HPV-associated tumors are not detected by HPV testing and will not be prevented by HPV vaccination. Malignant non-epithelial, and mixed epithelial/mesenchymal, tumors of the cervix occur but are rare.
|Title of host publication||Reference Module in Biomedical Sciences|
|Publication status||Published - 2017|