PEDANTICS: an R package for pedigree-based genetic simulation and pedigree manipulation, characterization and viewing

Michael B. Morrissey, Alastair J. Wilson

Research output: Contribution to journalArticlepeer-review

Abstract

Analyses of pedigrees and pedigree-derived parameters (e.g. relatedness and fitness) provide some of the most informative types of studies in evolutionary biology. The r package pedantics implements tools to facilitate power and sensitivity analyses of pedigree-related studies of natural populations. Functions are available to permute pedigree data in various ways with the goal of mimicking patterns of pedigree errors and missingness that occur in studies of natural populations. Another set of functions simulates genetic and phenotypic data based on arbitrary pedigrees. Finally, functions are also available with which visual and numerical representations of pedigree structure can be generated.

Original languageEnglish
Pages (from-to)711-719
Number of pages9
JournalMolecular Ecology Resources
Volume10
Issue number4
Early online date16 Dec 2009
DOIs
Publication statusPublished - 31 Jul 2010

Keywords

  • natural populations
  • pedigrees
  • power
  • quantitative genetics
  • uncertainty

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