Peptidoglycan synthesis in Salmonella typhimurium 2616

David Gally, S. Cooper

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

HPLC analysis of peptidoglycan synthesis in Salmonella typhimurium strain 2616 has revealed that: (i) there is observable variation in the composition, but no significant variation in the overall degree of cross-linking, of newly synthesized peptidoglycan during the division cycle; (ii) the types of muropeptide that constitute peptidoglycan do not vary over a wide range of growth rates; and (iii) the composition and maturation kinetics of S. typhimurium peptidoglycan are, as expected, similar to those of Escherichia coli. We propose a unitary model of peptidoglycan synthesis, with single-strand incorporation occurring at both side wall and polar sites.
Original languageEnglish
Pages (from-to)1469-76
Number of pages8
JournalJournal of General Microbiology
Issue number7
Publication statusPublished - Jul 1993

Keywords / Materials (for Non-textual outputs)

  • Cell division
  • Models, Biological
  • Peptidoglycan/biosynthesis
  • Peptidoglycan/chemistry
  • Salmonella typhimurium/chemistry
  • Salmonella typhimurium/growth & development
  • Salmonella typhimurium/metabolism
  • Time Factors


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