Perioperative elafin for ischaemiareperfusion injury during coronary artery bypass graft surgery: a randomisedcontrolled trial.

Alam SR, Lewis SC, Zamvar V, Pessotto R, Dweck MR, Krishan A, Goodman K, Oatey K, Harkess R, Milne L, Thomas S, Mills NM, Moore C, Semple S, Wiedow O, Stirrat C, Mirsadraee S, Newby DE, Henriksen PA.

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Elafin is a potent endogenous neutrophil elastase inhibitor that protects against myocardial inflammation and injury in preclinical models of ischaemic-reperfusion injury. We investigated whether elafin could inhibit myocardial ischaemia-reperfusion injury induced during coronary artery bypass graft (CABG) surgery
Original languageEnglish
Pages (from-to)1639-45
JournalHeart
Publication statusPublished - Oct 2015

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