Persistence of accuracy of genome-wide breeding values over generations when including a polygenic effect

Trygve R Solberg, Anna K Sonesson, John A Woolliams, Jørgen Odegard, Theo H E Meuwissen

Research output: Contribution to journalArticlepeer-review

Abstract

When estimating marker effects in genomic selection, estimates of marker effects may simply act as a proxy for pedigree, i.e. their effect may partially be attributed to their association with superior parents and not be linked to any causative QTL. Hence, these markers mainly explain polygenic effects rather than QTL effects. However, if a polygenic effect is included in a Bayesian model, it is expected that the estimated effect of these markers will be more persistent over generations without having to re-estimate the marker effects every generation and will result in increased accuracy and reduced bias.
Original languageEnglish
Pages (from-to)53
JournalGenetics Selection Evolution
Volume41
DOIs
Publication statusPublished - 2009

Keywords

  • Bayes Theorem
  • Genetic Drift
  • Genetic Markers
  • Linear Models
  • Linkage Disequilibrium
  • Models, Genetic
  • Multifactorial Inheritance
  • Mutation
  • Reproducibility of Results
  • Selection, Genetic

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