Phosphabarrelene-modified Rh-catalysts: a new and selective route towards hydroxy-functionalized bicyclic imidazoles via tandem reactions

Patrick S. Bauerlein, Ismael Arenas Gonzalez, Jarno J. M. Weemers, Martin Lutz, Anthony L. Spek, Dieter Vogt, Christian Muller

Research output: Contribution to journalArticlepeer-review

Abstract

8-Hydroxy-6-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine was formed selectively in high yields from N-(b-methallyl)imidazole by a tandem hydroformylation-cyclization sequence, representing a novel one-pot catalytic synthesis of bicyclic imidazole derivatives.

Original languageEnglish
Pages (from-to)4944-4946
Number of pages3
JournalChemical Communications
Issue number33
DOIs
Publication statusPublished - 2009

Cite this