Piecing together the puzzle of severe malaria

Aubrey J Cunnington, Michael Walther, Eleanor M Riley

Research output: Contribution to journalArticlepeer-review

Abstract

Severe malaria manifests as several overlapping syndromes with high mortality. Interaction of parasites with endothelial protein C receptors and high parasite biomass have recently been identified as key determinants of severe disease. However, gaps in our understanding of severe malaria might hinder translation of these findings into new therapies.

Original languageEnglish
Pages (from-to)211ps18
JournalScience Translational Medicine
Volume5
Issue number211
DOIs
Publication statusPublished - 13 Nov 2013

Keywords

  • Host-Parasite Interactions
  • Humans
  • Malaria/immunology
  • Plasmodium/classification
  • Severity of Illness Index

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