Piecing together the puzzle of severe malaria

Aubrey J Cunnington, Michael Walther, Eleanor M Riley

Research output: Contribution to journalArticlepeer-review


Severe malaria manifests as several overlapping syndromes with high mortality. Interaction of parasites with endothelial protein C receptors and high parasite biomass have recently been identified as key determinants of severe disease. However, gaps in our understanding of severe malaria might hinder translation of these findings into new therapies.

Original languageEnglish
Pages (from-to)211ps18
JournalScience Translational Medicine
Issue number211
Publication statusPublished - 13 Nov 2013


  • Host-Parasite Interactions
  • Humans
  • Malaria/immunology
  • Plasmodium/classification
  • Severity of Illness Index


Dive into the research topics of 'Piecing together the puzzle of severe malaria'. Together they form a unique fingerprint.

Cite this