Abstract
Severe malaria manifests as several overlapping syndromes with high mortality. Interaction of parasites with endothelial protein C receptors and high parasite biomass have recently been identified as key determinants of severe disease. However, gaps in our understanding of severe malaria might hinder translation of these findings into new therapies.
Original language | English |
---|---|
Pages (from-to) | 211ps18 |
Journal | Science Translational Medicine |
Volume | 5 |
Issue number | 211 |
DOIs | |
Publication status | Published - 13 Nov 2013 |
Keywords / Materials (for Non-textual outputs)
- Host-Parasite Interactions
- Humans
- Malaria/immunology
- Plasmodium/classification
- Severity of Illness Index