Abstract
Borenium does it direct: A boron analogue of the Friedel-Crafts reaction uses inexpensive catecholatoborenium cations that are sufficiently electrophilic to borylate arenes by electrophilic aromatic substitution. The direct arene borylation proceeds with high regioselectivity for a range of anilines, N-heterocycles, and thiophenes. Subsequent one-pot transesterification provides the synthetically useful pinacol boronate esters (see scheme).
Original language | English |
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Pages (from-to) | 2102-2106 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 50 |
Issue number | 9 |
DOIs | |
Publication status | Published - 25 Feb 2011 |
Keywords
- borenium ions
- borocations
- boronate esters
- borylation
- electrophilic substitution