Ploidy dynamics increase the risk of liver cancer initiation

Miryam Müller, Stephanie May, Thomas G. Bird

Research output: Contribution to journalArticlepeer-review

Abstract

Liver cancer typically arises after years of inflammatory insults to hepatocytes.
These cells can change their ploidy state during health and disease. Whilst
polyploidy may offer some protection, new research shows it may also promote
the formation of liver tumours.
Original languageEnglish
JournalNature Communications
Volume12
Issue number1
DOIs
Publication statusPublished - 25 Mar 2021

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