Polymer microarrays: Identification of substrates for phagocytosis assays

Alexandra Mant, Guilhem Tourniaire, Juan J. Diaz-Mochon, Tim J. Elliott, Anthony P. Williams, Mark Bradley

Research output: Contribution to journalArticlepeer-review

Abstract

A polymer microarray of 120 polyurethanes was used to identify polymers that promoted the adhesion of bone marrow dendritic cells (BMDC). Identified polymers were coated onto glass cover slips and shown to be efficient substrates for the immobilisation of these primary cells, which underwent efficient phagocytosis while still presumably maintaining their immature state. (c) 2006 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)5299-5306
Number of pages8
JournalBiomaterials
Volume27
Issue number30
DOIs
Publication statusPublished - Oct 2006

Keywords

  • dendritic cells
  • microarrays
  • polyurethane
  • cell adhesion
  • phagocytosis
  • CELL-ADHESION
  • DENDRITIC CELLS
  • ENDOTHELIAL-CELLS
  • NONADHERENT CELLS
  • CULTURE
  • FIBRONECTIN
  • ADSORPTION
  • ATTACHMENT
  • SURFACE

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