Polymer microarrays: Identification of substrates for phagocytosis assays

Alexandra Mant; Guilhem Tourniaire; Juan J. Diaz-Mochon; Tim J. Elliott; Anthony P. Williams; Mark Bradley

doi:10.1016/j.biomaterials.2006.04.040

Polymer microarrays: Identification of substrates for phagocytosis assays

Alexandra Mant, Guilhem Tourniaire, Juan J. Diaz-Mochon, Tim J. Elliott, Anthony P. Williams, Mark Bradley

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

A polymer microarray of 120 polyurethanes was used to identify polymers that promoted the adhesion of bone marrow dendritic cells (BMDC). Identified polymers were coated onto glass cover slips and shown to be efficient substrates for the immobilisation of these primary cells, which underwent efficient phagocytosis while still presumably maintaining their immature state. (c) 2006 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	5299-5306
Number of pages	8
Journal	Biomaterials
Volume	27
Issue number	30
DOIs	https://doi.org/10.1016/j.biomaterials.2006.04.040
Publication status	Published - Oct 2006

Keywords / Materials (for Non-textual outputs)

dendritic cells
microarrays
polyurethane
cell adhesion
phagocytosis
CELL-ADHESION
DENDRITIC CELLS
ENDOTHELIAL-CELLS
NONADHERENT CELLS
CULTURE
FIBRONECTIN
ADSORPTION
ATTACHMENT
SURFACE

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10.1016/j.biomaterials.2006.04.040

Interfacing DNA arrays and combinatorial libraries for high-content enzymatic screening
Bradley, M.
BBSRC
1/03/05 → 31/05/05
Project: Research

Cite this

@article{435b828e2cb34c3193362a4c2f96cbad,

title = "Polymer microarrays: Identification of substrates for phagocytosis assays",

abstract = "A polymer microarray of 120 polyurethanes was used to identify polymers that promoted the adhesion of bone marrow dendritic cells (BMDC). Identified polymers were coated onto glass cover slips and shown to be efficient substrates for the immobilisation of these primary cells, which underwent efficient phagocytosis while still presumably maintaining their immature state. (c) 2006 Elsevier Ltd. All rights reserved.",

keywords = "dendritic cells, microarrays, polyurethane, cell adhesion, phagocytosis, CELL-ADHESION, DENDRITIC CELLS, ENDOTHELIAL-CELLS, NONADHERENT CELLS, CULTURE, FIBRONECTIN, ADSORPTION, ATTACHMENT, SURFACE",

author = "Alexandra Mant and Guilhem Tourniaire and Diaz-Mochon, {Juan J.} and Elliott, {Tim J.} and Williams, {Anthony P.} and Mark Bradley",

year = "2006",

month = oct,

doi = "10.1016/j.biomaterials.2006.04.040",

language = "English",

volume = "27",

pages = "5299--5306",

journal = "Biomaterials",

issn = "0142-9612",

publisher = "Elsevier",

number = "30",

}

TY - JOUR

T1 - Polymer microarrays: Identification of substrates for phagocytosis assays

AU - Mant, Alexandra

AU - Tourniaire, Guilhem

AU - Diaz-Mochon, Juan J.

AU - Elliott, Tim J.

AU - Williams, Anthony P.

AU - Bradley, Mark

PY - 2006/10

Y1 - 2006/10

N2 - A polymer microarray of 120 polyurethanes was used to identify polymers that promoted the adhesion of bone marrow dendritic cells (BMDC). Identified polymers were coated onto glass cover slips and shown to be efficient substrates for the immobilisation of these primary cells, which underwent efficient phagocytosis while still presumably maintaining their immature state. (c) 2006 Elsevier Ltd. All rights reserved.

AB - A polymer microarray of 120 polyurethanes was used to identify polymers that promoted the adhesion of bone marrow dendritic cells (BMDC). Identified polymers were coated onto glass cover slips and shown to be efficient substrates for the immobilisation of these primary cells, which underwent efficient phagocytosis while still presumably maintaining their immature state. (c) 2006 Elsevier Ltd. All rights reserved.

KW - dendritic cells

KW - microarrays

KW - polyurethane

KW - cell adhesion

KW - phagocytosis

KW - CELL-ADHESION

KW - DENDRITIC CELLS

KW - ENDOTHELIAL-CELLS

KW - NONADHERENT CELLS

KW - CULTURE

KW - FIBRONECTIN

KW - ADSORPTION

KW - ATTACHMENT

KW - SURFACE

U2 - 10.1016/j.biomaterials.2006.04.040

DO - 10.1016/j.biomaterials.2006.04.040

M3 - Article

SN - 0142-9612

VL - 27

SP - 5299

EP - 5306

JO - Biomaterials

JF - Biomaterials

IS - 30

ER -

Polymer microarrays: Identification of substrates for phagocytosis assays

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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Projects

Interfacing DNA arrays and combinatorial libraries for high-content enzymatic screening

Cite this