Polymorphisms within the coding region of the bovine luteinizing hormone receptor gene and their association with fertility traits

N. Hastings, S. Donn, K. Derecka, A.P. Flint, John Woolliams

Research output: Contribution to journalArticlepeer-review

Abstract

Mutations within a number of genes have been associated with variations in fertility in various mammals. However, to date there have been no such associations reported for cattle. Herein, we describe three single nucleotide polymorphisms (SNPs) in the luteinizing hormone/choriogonadotropin receptor gene of cattle (Bos taurus). These polymorphisms include two missense mutations and one sense mutation, and all are located in areas of conserved synteny. When assessed in terms of haplotypes, these SNPs were significantly associated with variations in cattle fertility and production traits, most notably on calving interval, days to first service and production index (the UK economic index of milk yield measured in GB) pound.
Original languageUndefined/Unknown
Pages (from-to)583-585
Number of pages3
JournalAnimal Genetics
Volume37
Issue number6
Publication statusPublished - 2006

Keywords

  • bovine fertility LHCGR luteinizing hormone receptor cattle

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