Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells

Jeni Pinson; T Ian Simpson; John O Mason; David Price

doi:10.1186/1471-213X-6-25

Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells

Jeni Pinson, T Ian Simpson, John O Mason, David Price

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Pax6 is a transcription factor essential for normal development of the eyes and nervous system. It has two major isoforms, Pax6 and Pax6(5a), and the ratios between their expression levels vary within narrow limits. We tested the effects of overexpressing either one or other isoform on endogenous Pax6 expression levels in Neuro2A and NIH3T3 cells.

Original language	English
Article number	25
Number of pages	9
Journal	BMC Developmental Biology
Volume	6
DOIs	https://doi.org/10.1186/1471-213X-6-25
Publication status	Published - 2006

Access to Document

10.1186/1471-213X-6-25

1471-213X-6-25Final published version, 508 KB

Cite this

@article{e12857feadd6416787f48ba6446322af,

title = "Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells",

abstract = "Pax6 is a transcription factor essential for normal development of the eyes and nervous system. It has two major isoforms, Pax6 and Pax6(5a), and the ratios between their expression levels vary within narrow limits. We tested the effects of overexpressing either one or other isoform on endogenous Pax6 expression levels in Neuro2A and NIH3T3 cells.",

author = "Jeni Pinson and Simpson, {T Ian} and Mason, {John O} and David Price",

year = "2006",

doi = "10.1186/1471-213X-6-25",

language = "English",

volume = "6",

journal = "BMC Developmental Biology",

issn = "1471-213X",

publisher = "BioMed Central",

}

TY - JOUR

T1 - Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells

AU - Pinson, Jeni

AU - Simpson, T Ian

AU - Mason, John O

AU - Price, David

PY - 2006

Y1 - 2006

N2 - Pax6 is a transcription factor essential for normal development of the eyes and nervous system. It has two major isoforms, Pax6 and Pax6(5a), and the ratios between their expression levels vary within narrow limits. We tested the effects of overexpressing either one or other isoform on endogenous Pax6 expression levels in Neuro2A and NIH3T3 cells.

AB - Pax6 is a transcription factor essential for normal development of the eyes and nervous system. It has two major isoforms, Pax6 and Pax6(5a), and the ratios between their expression levels vary within narrow limits. We tested the effects of overexpressing either one or other isoform on endogenous Pax6 expression levels in Neuro2A and NIH3T3 cells.

U2 - 10.1186/1471-213X-6-25

DO - 10.1186/1471-213X-6-25

M3 - Article

C2 - 16725027

SN - 1471-213X

VL - 6

JO - BMC Developmental Biology

JF - BMC Developmental Biology

M1 - 25

ER -

Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells

Abstract / Description of output

Access to Document

Fingerprint

Cite this