Potential for gene editing in antiviral resistance

Douglas Pyott, Yue Fei, Attila Molnar

Research output: Contribution to journalBook/Film/Article reviewpeer-review

Abstract

The discovery of CRISPR/Cas systems and their subsequent application in genome modifications and in gene expression control have fundamentally changed both basic and applied research. They have already been employed to generate novel virus resistance traits either by modifying host factors in the plant genome or by directly inducing targeted virus degradation. Here we summarise the latest developments in this field and discuss the potential applications and concerns around this technology.
Original languageEnglish
Pages (from-to)47-52
JournalCurrent Opinion in Virology
Early online date5 Jun 2020
DOIs
Publication statusE-pub ahead of print - 5 Jun 2020

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