Potential of Genome Editing to Improve Aquaculture Breeding and Production

Remi Gratacap, Anna Wargelius, Rolf Brudvik Edvardsen, Ross Houston

Research output: Contribution to journalArticlepeer-review

Abstract

Aquaculture is the fastest growing food production sector and is rapidly becoming the primary source of seafood for human diets. Selective breeding programs are enabling genetic improvement of production traits, such as disease resistance, but progress is limited by the heritability of the trait and generation interval of the species. New breeding technologies, such as genome editing using CRISPR/Cas9 have the potential to expedite sustainable genetic improvement in aquaculture. Genome editing can rapidly introduce favorable changes to the genome, such as fixing alleles at existing trait loci, creating de novo alleles, or introducing alleles from other strains or species. The high fecundity and external fertilization of most aquaculture species can facilitate genome editing for research and application at a scale that is not possible in farmed terrestrial animals.
Original languageEnglish
JournalTrends in Genetics
Early online date19 Jul 2019
DOIs
Publication statusE-pub ahead of print - 19 Jul 2019

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