Power calculations in single-case neuropsychology: A practical primer

Robert McIntosh, Jonathan Rittmo

Research output: Contribution to journalArticlepeer-review

Abstract

Researchers and clinicians in neuropsychology often compare individual patients against healthy control samples, to quantify evidence for cognitive-behavioural deficits and dissociations. Statistical methods for these comparisons have been developed that control Type I (false positive) errors effectively. However, remarkably little attention has been given to the power of these tests. In this practical primer, we describe, in minimally technical terms, the origins and limits of power for case-control comparisons. We argue that power calculations can play useful roles in single-case study design and interpretation, and we make suggestions for optimising power in practice. As well as providing figures, tables and tools for estimating the power of case-control comparisons, we hope to assist researchers in setting realistic expectations for what such tests can achieve in general.
Original languageEnglish
Pages (from-to)146-158
JournalCortex
Volume135
Early online date3 Dec 2020
DOIs
Publication statusPublished - Feb 2021

Keywords

  • single case
  • deficit
  • dissociation
  • power
  • statistical methods

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