Pre-existing autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1

Paul Bastard; Elizaveta Orlova; Leila Sozaeva; Romain Lévy; Alyssa James; Monica M Schmitt; Sebastian Ochoa; Maria Kareva; Yulia Rodina; Adrian Gervais; Tom Le Voyer; Jérémie Rosain; Quentin Philippot; Anna-Lena Neehus; Elana Shaw; Mélanie Migaud; Lucy Bizien; Olov Ekwall; Stefan Berg; Guglielmo Beccuti; Lucia Ghizzoni

doi:https://doi.org/10.1084/jem.20210554

Pre-existing autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1

Paul Bastard, Elizaveta Orlova, Leila Sozaeva, Romain Lévy, Alyssa James, Monica M Schmitt, Sebastian Ochoa, Maria Kareva, Yulia Rodina, Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot, Anna-Lena Neehus, Elana Shaw, Mélanie Migaud, Lucy Bizien, Olov Ekwall, Stefan Berg, Guglielmo BeccutiLucia Ghizzoni

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Journal of Experimental Medicine
Early online date	23 Apr 2021
DOIs	https://doi.org/10.1084/jem.20210554
Publication status	E-pub ahead of print - 23 Apr 2021
Externally published	Yes

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© 2021 Bastard et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
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Cite this

Bastard, P., Orlova, E., Sozaeva, L., Lévy, R., James, A., Schmitt, M. M., Ochoa, S., Kareva, M., Rodina, Y., Gervais, A., Le Voyer, T., Rosain, J., Philippot, Q., Neehus, A-L., Shaw, E., Migaud, M., Bizien, L., Ekwall, O., Berg, S., ... Ghizzoni, L. (2021). Pre-existing autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1. Journal of Experimental Medicine. https://doi.org/10.1084/jem.20210554

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title = "Pre-existing autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1",

author = "Paul Bastard and Elizaveta Orlova and Leila Sozaeva and Romain L{\'e}vy and Alyssa James and Schmitt, {Monica M} and Sebastian Ochoa and Maria Kareva and Yulia Rodina and Adrian Gervais and {Le Voyer}, Tom and J{\'e}r{\'e}mie Rosain and Quentin Philippot and Anna-Lena Neehus and Elana Shaw and M{\'e}lanie Migaud and Lucy Bizien and Olov Ekwall and Stefan Berg and Guglielmo Beccuti and Lucia Ghizzoni",

year = "2021",

month = apr,

day = "23",

doi = "https://doi.org/10.1084/jem.20210554",

language = "English",

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Bastard, P, Orlova, E, Sozaeva, L, Lévy, R, James, A, Schmitt, MM, Ochoa, S, Kareva, M, Rodina, Y, Gervais, A, Le Voyer, T, Rosain, J, Philippot, Q, Neehus, A-L, Shaw, E, Migaud, M, Bizien, L, Ekwall, O, Berg, S, Beccuti, G & Ghizzoni, L 2021, 'Pre-existing autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1', Journal of Experimental Medicine. https://doi.org/10.1084/jem.20210554

TY - JOUR

T1 - Pre-existing autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1

AU - Bastard, Paul

AU - Orlova, Elizaveta

AU - Sozaeva, Leila

AU - Lévy, Romain

AU - James, Alyssa

AU - Schmitt, Monica M

AU - Ochoa, Sebastian

AU - Kareva, Maria

AU - Rodina, Yulia

AU - Gervais, Adrian

AU - Le Voyer, Tom

AU - Rosain, Jérémie

AU - Philippot, Quentin

AU - Neehus, Anna-Lena

AU - Shaw, Elana

AU - Migaud, Mélanie

AU - Bizien, Lucy

AU - Ekwall, Olov

AU - Berg, Stefan

AU - Beccuti, Guglielmo

AU - Ghizzoni, Lucia

PY - 2021/4/23

Y1 - 2021/4/23

U2 - https://doi.org/10.1084/jem.20210554

DO - https://doi.org/10.1084/jem.20210554

M3 - Article

JO - Journal of Experimental Medicine

JF - Journal of Experimental Medicine

SN - 0022-1007

ER -