Precision editing of large animal genomes

Wenfang Spring Tan; Daniel F Carlson; Mark W Walton; Scott C Fahrenkrug; Perry B Hackett

doi:10.1016/B978-0-12-404742-6.00002-8

Precision editing of large animal genomes

Wenfang Spring Tan, Daniel F Carlson, Mark W Walton, Scott C Fahrenkrug, Perry B Hackett

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Transgenic animals are an important source of protein and nutrition for most humans and will play key roles in satisfying the increasing demand for food in an ever-increasing world population. The past decade has experienced a revolution in the development of methods that permit the introduction of specific alterations to complex genomes. This precision will enhance genome-based improvement of farm animals for food production. Precision genetics also will enhance the development of therapeutic biomaterials and models of human disease as resources for the development of advanced patient therapies.

Original language	English
Pages (from-to)	37-97
Number of pages	61
Journal	Advances in Genetics
Volume	80
DOIs	https://doi.org/10.1016/B978-0-12-404742-6.00002-8
Publication status	Published - 2012

Keywords / Materials (for Non-textual outputs)

Animals
Animals, Domestic
Animals, Genetically Modified
Disease Models, Animal
Food Supply
Genetic Engineering
Genome
Humans
Meat

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10.1016/B978-0-12-404742-6.00002-8

Cite this

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title = "Precision editing of large animal genomes",

abstract = "Transgenic animals are an important source of protein and nutrition for most humans and will play key roles in satisfying the increasing demand for food in an ever-increasing world population. The past decade has experienced a revolution in the development of methods that permit the introduction of specific alterations to complex genomes. This precision will enhance genome-based improvement of farm animals for food production. Precision genetics also will enhance the development of therapeutic biomaterials and models of human disease as resources for the development of advanced patient therapies.",

keywords = "Animals, Animals, Domestic, Animals, Genetically Modified, Disease Models, Animal, Food Supply, Genetic Engineering, Genome, Humans, Meat",

author = "Tan, {Wenfang Spring} and Carlson, {Daniel F} and Walton, {Mark W} and Fahrenkrug, {Scott C} and Hackett, {Perry B}",

year = "2012",

doi = "10.1016/B978-0-12-404742-6.00002-8",

language = "English",

volume = "80",

pages = "37--97",

journal = "Advances in Genetics",

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T1 - Precision editing of large animal genomes

AU - Tan, Wenfang Spring

AU - Carlson, Daniel F

AU - Walton, Mark W

AU - Fahrenkrug, Scott C

AU - Hackett, Perry B

PY - 2012

Y1 - 2012

N2 - Transgenic animals are an important source of protein and nutrition for most humans and will play key roles in satisfying the increasing demand for food in an ever-increasing world population. The past decade has experienced a revolution in the development of methods that permit the introduction of specific alterations to complex genomes. This precision will enhance genome-based improvement of farm animals for food production. Precision genetics also will enhance the development of therapeutic biomaterials and models of human disease as resources for the development of advanced patient therapies.

AB - Transgenic animals are an important source of protein and nutrition for most humans and will play key roles in satisfying the increasing demand for food in an ever-increasing world population. The past decade has experienced a revolution in the development of methods that permit the introduction of specific alterations to complex genomes. This precision will enhance genome-based improvement of farm animals for food production. Precision genetics also will enhance the development of therapeutic biomaterials and models of human disease as resources for the development of advanced patient therapies.

KW - Animals

KW - Animals, Domestic

KW - Animals, Genetically Modified

KW - Disease Models, Animal

KW - Food Supply

KW - Genetic Engineering

KW - Genome

KW - Humans

KW - Meat

U2 - 10.1016/B978-0-12-404742-6.00002-8

DO - 10.1016/B978-0-12-404742-6.00002-8

M3 - Article

C2 - 23084873

SN - 0065-2660

VL - 80

SP - 37

EP - 97

JO - Advances in Genetics

JF - Advances in Genetics

ER -

Precision editing of large animal genomes

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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Cite this